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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83fc62ba4a4c5feae31b5e99caea57b98b1353960b963dc096109984ac49a395' 
  AND token = 'lK66FRsRTm6G2N2/plc8d9y4qQF7gVWDXTm/kpQz7TE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}