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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab5b2cbdf69121dded1e00c65a1cd37a365394e38cac8b5547a38d9b71aec0c6' 
  AND token = 'XLBf6A+OjbunwqlbNinWnH+l25u2uZNOxeortumT5yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}