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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3ff9900ef7dcfedfda488114add0a145188334f3d2b4bc9cd220bf82acf27d1' 
  AND token = 'ep3Ll/hoPO7sIX6GaSE7E1VbL/MhV0g2qyvsGpQrf+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}