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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c5e1dd7881579a6c460026626d3a8c7b625fa0fc003c5a42fecdf7b6f17b9ec' 
  AND token = 'WvSdQilV3UA+NMWsYUAjwtf8mwRfMIxR/LwJoA2jalM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}