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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0ce8ca838a63af24e82f2733f5b661ca0fa90ecddb9f8735d336ba6c313e8f4' 
  AND token = 'du8s3Ex+3i0bJYDhQZvL7NGQxDxese5rEE+Qwl3BEb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}