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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '295352ad4d8e658afb0ebe08a51214bb88c8830fb62ea8e9a93878fd6ead42d5' 
  AND token = '2dVGQtiDaprjj1TB8rUdDW5sGjjFW7wl+pqyOzdhPpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}