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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bc85a8d85dd0e012f379965f36d69c5cf7468f2eeea7022a11b125f89bbfb06' 
  AND token = 'StO8d7pLrv0cjEWL8YE8/EW1v5NUeeGkwG9D1wrxAGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}