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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85a228724b213146342300d74e7d47bcbe3428c5012a0a5fe7a6663a86b7d5da' 
  AND token = 'sCIOgDSvXUCkns6ePubzUQ8TekOCAMK0r4RZTc6wcDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}