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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6db0ab2f041d6235b8c62eb2e6fd1c052d481994331ea87243d28399ef771f83' 
  AND token = 'oxEPTms6ISvisYiAh/t68p3qARmSkhF0EOuD5Qc+Cvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}