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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0c8af62bf2f76dda0521c8180ecb1930a8209df0f053f9d898f0f754fb3f6d4' 
  AND token = 'yhIR8CrlfBfsgHxsJDG3ix9yzAuBSTSuh0MRHLkuaV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}