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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c9e8749c1c70f29c6ef379b1fb7478738059f52ffb0f0f1e7e53b627b402af4' 
  AND token = 'u388FHe9kfvlrRhA0ilAjDWfLC4A+zDAXq2BIxTyusg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}