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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d6d81f12650844f5de2cdf101b7f56c01fefc8f430e457d0e027e4ab0db4da7' 
  AND token = 'U78lPVA8sCdIs25mCj9u1V6uToL+cbx4oqCIiuiuFp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}