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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efe41950dcf1836bb4a42c0c712a1238a690c34eec55e30b72d3433a25caf5c2' 
  AND token = 'cTes0aMDWsKyx/lnyb6R+5RByXpZPeLlhfpjrs8NUII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}