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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af7cf200ca99e566dddb55ea38bf32551497213c28d8c7539d2ad476a307c959' 
  AND token = 'W72qFr2nxez+Vt9cj26API9Jax3qTJo50ZSfSjsTOEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}