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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10bbdc8d7484e8a8f3a6b7e25858a025ba7a396bda053d7f2efb91b5a3e6fa2e' 
  AND token = 'yQ3EHInGd7vtxiNtOZjbjbvMFQOi5SsyCBPKVQUqiPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}