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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4c2190a654243e37bb1b18f53012c2d8e1f5bcb0cc1c91d0443f3899a69414e' 
  AND token = 'yHIfgph+NkYLwmGGOT+sWW0oX2ajzJlW2kMTqSWCqGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}