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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c4e2406d983ae70d895b4ddd154c05ff1ab4f11842e2b24ae4337233ccb2e45' 
  AND token = 'TGdiPcRY743rLec+Yz0IiG1yYhZeMFehJbl9VLrzdIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}