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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c95f0e75e308e43c5148d8300b19158e0d39e3144970a1462fa70018e161dc8d' 
  AND token = 's1Rrwd1uAzqX1YIXvBYMNfmIwhpSHljFEjsagbBH1Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}