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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6ef59eaaeb56b106cc9365d5ae00e2a733cdb8f0d975526264845419a6a0193' 
  AND token = 'KqCV55DGd/stdEBOtU8t+mcR4PsztkKxRiUlkog0dW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}