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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29a761d73a8c008a6ed14b902debdfca214300998400dcd85da987b84b0d1bdb' 
  AND token = '2IQckyZEMj1caigrVWo1u7f7ag80IEPSnfE7OH5NSxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}