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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd21e1378be429e94226980a273b220cac81aa7f274bdd1f5f23298e27317f9c' 
  AND token = 'MZ/+kgPoV8sFl6MD3Od5RyQ/7ogN8ujS3vDv+mSsjo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}