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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d9a0d2a6ef66525fe7cdc901d9853c64baece4998e40815e5866d47578534c' 
  AND token = '+YtfDyo8UOGRCrQn3VPUccN6fHZextXMnrIuWOST+pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}