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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e1aa21dfe8d5b0f9929a9d91f270b4a4d6edbc603e3006e812b81993e89757e' 
  AND token = 'fW77seDDGEAf5avCCqfSAQq/eYXo3K7JqP/PFQckC18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}