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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bb01fd2d0278304ad4c55614f4bddf844ac16390197d1b5e7b1e8cd25ea60f7' 
  AND token = 'vK9ncaxiPGkZqKhXsGr3xZ7Y4UrfXRZCfv1+vluY2sI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}