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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '662a6c61d68302cffffadda6f066e8c31201a1cf32d337c2f7d7f4d0ea55a072' 
  AND token = 'yL34LPTAqHVBfmbL4D7lUH6X6/gAg/jr5W6B0+HkZPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}