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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e26423f872df26c52a5e1bf01eb69ec2807b5cc0d4de7ee31ec53451bd2886a' 
  AND token = '0x9jSJKA34M6BMR2k+Y3sT8JpttQQUf/Orl/ZY0VG/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}