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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d168a068b0ea0617a460c3f2d5cbb14c29893ef69366ae01aff4992337eead' 
  AND token = '3m2sYwtTH+XDP3igfV1eQPyuSYnzuabbECYshgM8xZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}