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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3181b14ae9c0bc4fc4d2f9f3f72455cde21f2427a8c22efc3e20e0032573ce8a' 
  AND token = 'z45gZuRcWhQfobG+GBGHgWHuh2My5NSy6JlqZ7PJQpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}