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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e4072137b2ab5ef85f0a490433506ed71d6de574f70fa391ca05dbba9d6ee5' 
  AND token = 'QOkHb5VWykPnwp9xq2hECfzBOxAFoXk1FWGE5yP/K8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}