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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1641a155a2d20832b5f8ee79d772763b194ea84859fe4272f0b453864808071' 
  AND token = 'kugR4EFhrxy7+1DEXElvty7vW8zyC1k0xIfebKaYnUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}