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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41bb7159e4f0bb18bf2e12c57ca3a5fa87380ff1c511c0ed25ab710b769b5b90' 
  AND token = '4V78oPOSCOtGA2L7yCg+Qi2gsi4ssB9+C+2CAUZb3lY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}