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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aebd449a9eb35e0419d6eccb518a27b6106c014b551597478c5833fe6e56c6e' 
  AND token = 'EK39jNjP+0q19xkMploXrM6VO8347Nqw3R2h2loALXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}