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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3f157841913e1bba744bb53dbf9bd0c4571eefe6c0682edb60bccfac7fafce6' 
  AND token = 'Kvy0A//mf8P9bC7n1/b4WlUIhuaeUvCB+5vtMYAfSs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}