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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f6ac783ab494c7241fa000b1279dc51415b100adf62b4795daf0e9a4a6ece0e' 
  AND token = 'OMaJunbImr0w7iJTSJppAbe1F0ecF00NIBbPoxVxhKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}