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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad2599a9cca9392d9bae6f510af6c15e38eef01f7824cf0b831b2d04e901413b' 
  AND token = '1sVRX030KrpbfGn6kNHe49hBLyur9oq7iuLNxS1rf7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}