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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07da7f1cb40155399e8f72317f3ba95b598cf79bc4d461da1a483221f8869de3' 
  AND token = 'D3dNtN31XJ7+A9yQ+DkmPSbfDV+x3Dr6azfVxq2uR44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}