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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78f018d7cfe76f0756baa38e5d04ac9f5e18d77b7d35126f9e0e0ed9b9ec224' 
  AND token = 'CUuS2FamkCXFiEKbZ0hEcocJ7qLx/SzhCluPZuPgrWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}