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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '085729358a0fec399735b6948ea6c43fe79d8939e559cb89963f0c571549b1c7' 
  AND token = 'u1dW6SUDmM0Do/iz3btXmoH4sukc2nf5NfwVQiuV8JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}