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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '073f9da39a0134e61d56c9b76afa4ae2433cc3ad2f10f0f6464e749a87fb1379' 
  AND token = 'Nn/pgmnaN4s7x5JHNkYHDS7dI5pf3O2i8wewD6EMa+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}