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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ae94ab097521ecea6b95ee9c4db3e8cb24fd6afcb011df8c4ce427abe5b61a7' 
  AND token = 'kVt8E1Beu0rUgHdQlFsul1qt5Zlrjrkw++H2hyeFEko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}