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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e3cbf9eceff5a844ef5c7a1d3ae4e3c23b64c1926721fe0dbce58c2d29a059' 
  AND token = 'LOM9uUGD7WTPgX1kHiN9C0RRUlwi5C7SCV1lz7L4+Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}