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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f30be94c279beeaeea589b9d6a740557690b21b6d38396fae3db8e0c68a5c2' 
  AND token = 'jJ+4+w0SUgvsg6r03hZ8k4b2hpH3RCoYSduNugTkUEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}