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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c05cd0c48f61f7e705a31fa62718d5a5e6c6823bef622cca719c34d927f5cf9' 
  AND token = 'hxVJ042hkkrmUBCOCYt+nP3qZdInkN1wfuan+f8SNQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}