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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8db50c6281e3e8add7981f00815862f7834232e88f727396f9b865d43e2cf89' 
  AND token = '+4h+6UF6sSuD2a+r0Db8D4r3fLXbVSkdlmkBKD7dQM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}