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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f15608f0f174bd446c5d5e418627cbd8890a13001b9dc45958216bd0f7e730' 
  AND token = 'EnQcHufGXuF+1pY0G1Uc7/14EgyWVmr9qgpllQXCITU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}