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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4821dad6f67f10819697d35694bc766717ea456c502f9f9a66b2eac4d3f68362' 
  AND token = 'ujsCB6KjOYObPr8zJ2e3OBBx1u40DRdd6YHsnktTVO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}