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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '643598f12256dc06e87329d97c6c3f586544dff341d96ca42a947bd165fdfc32' 
  AND token = 'cpPA0mlRJboXSdeOksUvvR1LXihEPWBr29PUX7mnEIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}