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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8c28ddafaef29e604a9d6e2f4550716dd298c5d56c94ef4ab08e7ccca724e53' 
  AND token = 'XGD+8RTGwfKxzIvKtR6tFZPSSoh9ii1YF7/p191Mepo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}