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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6706128d4b3a6c8a87c2fb9a1a189cf3e52fd6b975d5bf6a03c875ee2cbd226f' 
  AND token = 'XU9rrMOv56YYa76LiRBciO0p3oa3RUMTcIFIeB5CS8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}