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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b4201001ccd67d59a65e3f29429370c2f1b441b1955a04c23d838ed43698ddf' 
  AND token = 'd8nx4Yre4qx5gERNyLTLJzhCC0U9GsNVE9YFeGSaXP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}